Chronic kidney disease in the BCR-ABL1-negative myeloproliferative neoplasm: a single-center retrospective study
نویسندگان
چکیده
منابع مشابه
Mutational Analysis of SH2B3 in Korean Patients With BCR-ABL1 Negative Myeloproliferative Neoplasm
Namhee Kim, M.D., In-Suk Kim, M.D., Chulhun Ludgerus Chang, M.D., Eun Yup Lee, M.D., Hyung Hoi Kim, M.D., Moo-Kon Song, M.D., Ho-Jin Shin, M.D., and Joo Seop Chung, M.D. Department of Laboratory Medicine, Pusan National University School of Medicine, Pusan National University Yangsan Hospital, Yangsan; Research Institute for Convergence of Biomedical Science and Technology, Pusan National Unive...
متن کاملCurrent pre-clinical and clinical advances in the BCR-ABL1-positive and -negative chronic myeloproliferative neoplasms.
Immunosenescence is an ill-defined term commonly used to describe the differences observed between younger and older individuals in a broad range of immune parameters. Humans and mice are the best-studied, but indications of immunosenescence have also been reported in primates, dogs, cats and horses. Although often referred to as age-associated changes to immunity, and almost always assumed to ...
متن کاملMyeloproliferative Disorders BCR-ABL1—Negative Myeloproliferative Neoplasms: A Review of Molecular Biology, Diagnosis, and Treatment
In 2008, the World Health Organization expanded the classification of myeloproliferative disorders based on increasing amounts of molecular and cytogenetic data. Myeloproliferative neoplasms (MPN) that do not contain the BCR-ABL1 mutation include polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF). JAK2V617F is the best characterized mutation in BCR-ABL1–nega...
متن کاملComparative study of different methodologies to detect the JAK2 V617F mutation in chronic BCR-ABL1 negative myeloproliferative neoplasms
OBJECTIVES A mutation in the JAK2 gene, V617F, has been identified in several BCR-ABL1 negative myeloproliferative neoplasms (MPN): polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF). Defining the presence or absence of this mutation is an essential part of clinical diagnostic algorithms and patient management. Here, we aimed to evaluate the performance of t...
متن کاملRisk-Reducing Genetic Variant of Wilms Tumor 1 Gene rs16754 in Korean Patients With BCR-ABL1-Negative Myeloproliferative Neoplasm
The genetic variant rs16754 of Wilms tumor gene 1 (WT1) has recently been described as an independent prognostic factor in AML patients. It is of great interest to test whether WT1 single nucleotide polymorphism can be used as a molecular marker in other types of cancer, to improve risk and treatment stratification. We performed sequencing analysis of exons 7 and 9 of WT1, which are known mutat...
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ژورنال
عنوان ژورنال: The Korean Journal of Internal Medicine
سال: 2018
ISSN: 1226-3303,2005-6648
DOI: 10.3904/kjim.2016.263